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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDH2
All Species:
0
Human Site:
S10
Identified Species:
0
UniProt:
P40926
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P40926
NP_005909.2
338
35503
S10
S
A
L
A
R
P
A
S
A
A
L
R
R
S
F
Chimpanzee
Pan troglodytes
XP_001156205
338
35499
Rhesus Macaque
Macaca mulatta
XP_001114888
374
39932
Dog
Lupus familis
XP_849944
338
35431
Cat
Felis silvestris
Mouse
Mus musculus
P08249
338
35593
Rat
Rattus norvegicus
P04636
338
35665
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415765
351
36949
Frog
Xenopus laevis
NP_001085326
338
35691
Zebra Danio
Brachydanio rerio
NP_998296
337
35401
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650696
336
35299
Honey Bee
Apis mellifera
XP_392478
338
35783
Nematode Worm
Caenorhab. elegans
O02640
341
35101
Sea Urchin
Strong. purpuratus
XP_792004
337
35239
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SN86
403
42387
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
85.8
93.1
N.A.
94.9
94.3
N.A.
N.A.
84.3
84
84.6
N.A.
58.8
65
56.8
68.3
Protein Similarity:
100
100
88.5
97
N.A.
98.2
97.9
N.A.
N.A.
91.1
92
93.1
N.A.
76.3
80.7
72.7
83.1
P-Site Identity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
0
P-Site Similarity:
100
0
0
0
N.A.
0
0
N.A.
N.A.
0
0
0
N.A.
0
0
0
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
50.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
100
0
100
0
0
100
0
100
100
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
100
0
0
0
0
0
0
0
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
100
0
0
0
0
0
0
100
100
0
0
% R
% Ser:
100
0
0
0
0
0
0
100
0
0
0
0
0
100
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _